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Basic information |
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Design and synthesis of chiral 1,10-phenanthroline ligand, and application in palladium catalyzed asymmetric 1,4-addition reactions
Masafumi Tamura, Hayato Ogata, Yuu Ishida, Yasunori Takahashi
Pd-catalyzed asymmetric 1,4-addition of phenylboronic acid to a,b-unsaturated carbonyl compounds was developed using chiral 1,10-phenanthroline derivative as ligand. Good yields (up to 97%), and high enantioselectives (up to 97% ee) were achieved.
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