著作(論文等)

Basic information

Name TAMURA Masafumi

論文名

Enantioselective construction of ortho-substituted benzylic quaternary centers using a phenanthroline-Pd catalyst

著者名

Maasafumi Tamura

掲載誌名等

Organic & Biomolecular Chemistry

掲載年月

2022-10

20

 

開始頁

8425

 

ENG

終了頁

8429

出版者(日本語)

 

出版者(英語)

RSC

発表形態

査読付き論文

概要

A method for Pd-catalyzed asymmetric conjugate addition of ortho-substituted arylboronic acids to cyclic enones was developed. The addition of various ortho-substituted arylboronic acid to β-substituted cyclic enones, via catalysis with a chiral phenanthroline-Pd complex, formed cyclic ketone products bearing ortho-substituted benzylic all-carbon quaternary centers with good yields and high enantioselectivity.