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基本情報
| 氏名 |
中川 直 |
| 氏名（カナ） |
ナカガワ タダシ |
| 氏名（英語） |
NAKAGAWA Tadashi |
| 所属 |
山陽小野田市立山口東京理科大学薬学部薬学科 |
| 職名 |
講師 |
| researchmap研究者コード |
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| researchmap機関 |
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- ALS-associated RNA binding proteins converge on UNC13A transcription through regulation of REST. EMBO Journal 2025/08
- Unique compound with anti-allergic action: inhibition of kinase activity of Lyn by KIRA6 Frontiers in Pharmacology 2025/08
- KBG syndrome-associated protein ANKRD11 regulates SETD5 expression to modulate rRNA levels and translation. iScience 2025/05
- Cullin-RING Ubiquitin Ligases in Neurodevelopment and Neurodevelopmental Disorders Biomedicines 2025/03
- The Molecular Intersection of NEK1, C21ORF2, Cyclin F, and VCP in ALS Pathogenesis Genes 2025/03
- Phosphodegrons in Health and Disease: From Cellular Homeostasis to Therapeutic Potential Kinases and Phosphatases 2025/02
- Heme regulates protein interactions and phosphorylation of BACH2 intrinsically disordered region in humoral response iScience 2025/01
- Pancreatic β cell-secreted factor FGF23 attenuates Alzheimer's disease-related amyloid β-induced neuronal death PNAS nexus 2025/01
- CUL4-Based Ubiquitin Ligases in Chromatin Regulation: An Evolutionary Perspective Cells 2025/01
- Midnolin, a Genetic Risk Factor for Parkinson’s Disease, Promotes Neurite Outgrowth Accompanied by Early Growth Response 1 Activation in PC12 Cells Molecular and Cellular Biology 2024/09
- TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22 International Journal of Molecular Sciences 2024/04
- Recent progress on action and regulation of anorexigenic adipokine leptin Frontiers in Endocrinology 2023/07
- Neurobehavioral characteristics of mice with SETD5 mutations as models of IDD23 and KBG syndromes Frontiers in Genetics 2023/01
- C-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer's cell model Am J Physiol Cell Physiol . 2022/12
- 肥満病態におけるレプチン抵抗性成立に対するアルデヒド類の影響 アグリバイオ 2022/06
- Insulin Enhances Gene Expression of Midnolin, a Novel Genetic Risk Factor for Parkinson's Disease, via Extracellular Signal-Regulated Kinase, Phosphoinositide 3-Kinase and Multiple Transcription Factors in SH-SY5Y Cells J Pharmacol Exp Ther . 2022/05 382 2 68 ～ 78
- SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones Cell Reports 2022/03
- Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations Stem Cell Reports . 2021/06
- USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2 Science Advances 2020/09/01
- An Amyotrophic Lateral Sclerosis–Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO3 iScience 2020/08/21
- The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression Iscience 2020/04/06
- Knockout Mouse Models Provide Insight into the Biological Functions of CRL1 Components Cullin-RING Ligases and Protein Neddylation 2020/01
- Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity Human Molecular Genetics 2019/10/15
- Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons EBioMedicine 2019/07/01
- The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice Developmental biology 2019/01/15
- Vpr targets TET2 for degradation by CRL4VprBP E3 ligase to sustain IL-6 expression and enhance HIV-1 replication Molecular cell 2018/06/07
- Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing Genetics in Medicine 2018/05
- Transforming growth factor β-induced proliferative arrest mediated by TRIM26-dependent TAF7 degradation and its antagonism by MYC Molecular and cellular biology 2018/03/01
- Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells Development 2017/11/15
- Ubiquitylation of Ku80 by RNF126 promotes completion of nonhomologous end joining-mediated DNA repair Molecular and cellular biology 2017/02/15
- The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis Science Signaling 2017/01/03
- S6 kinase-and β-TrCP2-dependent degradation of p19Arf is required for cell proliferation Molecular and cellular biology 2015/10/15
- Protein monoubiquitylation: targets and diverse functions Genes to Cells 2015/07
- ユビキチンリガーゼ複合体CRL4VprBPはTETタンパク質のモノユビキチン化およびクロマチンとの結合を促進する. ライフサイエンス新着論文レビュー 2015/02
- CRL4VprBP E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases Molecular cell 2015/01/22
- Variants in CUL4B are Associated with Cerebral Malformations Human mutation 2015/01
- VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases BMC molecular biology 2013/12
- Chromatin regulation by CRL4 E3 ubiquitin ligases: CUL4B targets WDR5 ubiquitylation in the nucleus Cell Cycle 2011/12/15
- X染色体性知的障害の原因タンパク質CUL4BはWDR5のユビキチン化にはたらくことで神経に特異的な遺伝子の発現を制御する. ライフサイエンス新着論文レビュー 2011/09
- X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression Molecular cell 2011/08/05
- X連鎖性知的障害原因タンパク質CUL4BはH3K4メチル化酵素複合体構成タンパク質WDR5をユビキチン化し神経遺伝子発現を制御する. 細胞工学 2011/07
- Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene Oncogene 2011/04
- CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis Nature cell biology 2009/02
- GMEB1, a novel endogenous caspase inhibitor, prevents hypoxia-and oxidative stress-induced neuronal apoptosis Neuroscience letters 2008/06/13
- Anchoring of the 26S proteasome to the organellar membrane by FKBP38 Genes to Cells 2007/06
- UFD経路. 蛋白質核酸酵素「ユビキチン―プロテアソーム系とオートファジー」 2007/02
- Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin‐dependent degradation Cancer science 2006/08
- Glucocorticoid modulatory element-binding protein 1 binds to initiator procaspases and inhibits ischemia-induced apoptosis and neuronal injury Journal of biological chemistry 2006/04/21
- Mammalian E4 is required for cardiac development and maintenance of the nervous system Molecular and cellular biology 2005/12/15
- Regulation of procaspase-2 by glucocorticoid modulatory element-binding protein 1 through the interaction with caspase recruitment domain Biochemical and biophysical research communications 2004/12/24
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